Sialic Acid: A Pivotal Component in the Glycobiology Universe

N-acetylneuraminic acid (sialic acid),dha algae oil supplier,Nutrition and health functional ingredients

N-acetylneuraminic acid (sialic acid) is a monosaccharide that is abundant on vertebrate glycoproteins, glycolipids, and milk oligosaccharides. It has a range of functional roles, from cell-cell interactions to immune system modulation. Sialic Acid is a subset of nonulosonic acids (NulOs), a family of 9-carbon backbone monosaccharides that also includes bacterial and archaeal variants.

Biosynthesis and Functional Complexity

The biosynthesis of NulO-glycans involves the activation of N-Acetylneuraminic Acid to a CMP-sugar derivative, which is then transferred to glycan acceptors. The presence of various functional groups and the potential for modifications and linkages contribute to the complexity and information-carrying capacity of these molecules.

Historical Discovery and Classification

The discovery of Sialic Acid dates back to its isolation from salivary mucins and brain glycolipids. The term "sialic acid" has persisted since its initial discovery and is now used to describe a family of related structures, including the most common form in humans, sialic acid.

The Sialic Acid Family and Its Properties

sialic acid is characterized by its strong acidity and distinctive structural features, such as the exocyclic glycerol-like side chain and the N-acetyl group. These properties influence its interactions and functions within biological systems.

Sialoglycan Diversity and Cellular Functions

The sialoglycans, or the "sialome," represent the sum of diverse Sialic Acid-containing structures on a cell. Modifications of Sialic Acid can alter its recognition by binding proteins and its overall function within the cell.

dha algae oil supplier and Health Ingredients

As a DHA Algae Oil Supplier, there is a focus on identifying Nutrition and health functional ingredients. Sialic Acid, with its multifaceted biological roles, is a key area of interest for potential nutritional and health applications.

The Expanding Role of Sialic Acid

The role of Sialic Acid in biological systems is expansive and continues to be a subject of extensive research. Its presence in various cellular structures and its potential health benefits make it a vital component in the field of glycobiology and nutritional science.


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